FAM129A

Protein-coding gene in the species Homo sapiens
NIBAN1
Identifiers
AliasesNIBAN1, C1orf24, NIBAN, GIG39, family with sequence similarity 129 member A, niban apoptosis regulator 1, FAM129A
External IDsMGI: 2137237; HomoloGene: 62170; GeneCards: NIBAN1; OMA:NIBAN1 - orthologs
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for NIBAN1
Genomic location for NIBAN1
Band1q25.3Start184,790,724 bp[1]
End184,974,508 bp[1]
Gene location (Mouse)
Chromosome 1 (mouse)
Chr.Chromosome 1 (mouse)[2]
Chromosome 1 (mouse)
Genomic location for NIBAN1
Genomic location for NIBAN1
Band1|1 G1- G2Start151,446,937 bp[2]
End151,597,690 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • saphenous vein

  • parotid gland

  • right ventricle

  • vena cava

  • myocardium

  • cardiac muscle tissue of right atrium

  • myocardium of left ventricle

  • Skeletal muscle tissue of rectus abdominis

  • seminal vesicula

  • right coronary artery
Top expressed in
  • iris

  • ciliary body

  • granulocyte

  • calvaria

  • ascending aorta

  • ankle

  • lumbar spinal ganglion

  • aortic valve

  • conjunctival fornix

  • lacrimal gland
More reference expression data
BioGPS


More reference expression data
Gene ontology
Molecular function
  • protein binding
  • molecular function
Cellular component
  • cytoplasm
  • plasma membrane
  • extracellular exosome
  • membrane
  • cytosol
Biological process
  • negative regulation of protein phosphorylation
  • positive regulation of protein phosphorylation
  • regulation of translation
  • positive regulation of translation
  • response to endoplasmic reticulum stress
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

116496

63913

Ensembl

ENSG00000135842

ENSMUSG00000026483

UniProt

Q9BZQ8

Q3UW53

RefSeq (mRNA)

NM_052966

NM_022018

RefSeq (protein)

NP_443198

NP_071301

Location (UCSC)Chr 1: 184.79 – 184.97 MbChr 1: 151.45 – 151.6 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Protein Niban is a protein that in humans is encoded by the FAM129A gene.[5][6][7] Paralogs of this protein include FAM129B, and FAM129C.[8]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000135842 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026483 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Cerutti JM, Delcelo R, Amadei MJ, Nakabashi C, Maciel RM, Peterson B, Shoemaker J, Riggins GJ (Apr 2004). "A preoperative diagnostic test that distinguishes benign from malignant thyroid carcinoma based on gene expression". J Clin Invest. 113 (8): 1234–42. doi:10.1172/JCI19617. PMC 385398. PMID 15085203.
  6. ^ Maciel RM, Kimura ET, Cerutti JM (Jan 2006). "[Pathogenesis of differentiated thyroid cancer (papillary and follicular)]". Arq Bras Endocrinol Metabol. 49 (5): 691–700. doi:10.1590/S0004-27302005000500009. PMID 16444351.
  7. ^ "Entrez Gene: FAM129A family with sequence similarity 129, member A".
  8. ^ "NIBAN1 Gene - GeneCards | NIBA1 Protein | NIBA1 Antibody".

Further reading

  • Majima S, Kajino K, Fukuda T, et al. (2000). "A novel gene "Niban" upregulated in renal carcinogenesis: cloning by the cDNA-amplified fragment length polymorphism approach". Jpn. J. Cancer Res. 91 (9): 869–74. doi:10.1111/j.1349-7006.2000.tb01027.x. PMC 5926447. PMID 11011112.
  • Sood R, Bonner TI, Makalowska I, et al. (2001). "Cloning and characterization of 13 novel transcripts and the human RGS8 gene from the 1q25 region encompassing the hereditary prostate cancer (HPC1) locus". Genomics. 73 (2): 211–22. doi:10.1006/geno.2001.6500. PMID 11318611.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
  • Matsumoto F, Fujii H, Abe M, et al. (2007). "A novel tumor marker, Niban, is expressed in subsets of thyroid tumors and Hashimoto's thyroiditis". Hum. Pathol. 37 (12): 1592–600. doi:10.1016/j.humpath.2006.06.022. PMID 16949643.


  • v
  • t
  • e