DUSP19 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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3S4E, 4D3P, 4D3R, 4D3Q |
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Identifiers |
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Aliases | DUSP19, DUSP17, LMWDSP3, SKRP1, TS-DSP1, dual specificity phosphatase 19 |
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External IDs | OMIM: 611437; MGI: 1915332; HomoloGene: 41565; GeneCards: DUSP19; OMA:DUSP19 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 2 (human)[1] |
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| Band | 2q32.1 | Start | 183,078,559 bp[1] |
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End | 183,100,008 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 2 (mouse)[2] |
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| Band | 2|2 C3 | Start | 80,447,389 bp[2] |
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End | 80,462,705 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - oocyte
- secondary oocyte
- buccal mucosa cell
- gonad
- bronchial epithelial cell
- testicle
- islet of Langerhans
- Descending thoracic aorta
- mucosa of paranasal sinus
- ventricular zone
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| Top expressed in | - medullary collecting duct
- condyle
- endocardial cushion
- Paneth cell
- lumbar subsegment of spinal cord
- endothelial cell of lymphatic vessel
- sternocleidomastoid muscle
- fossa
- right ventricle
- digastric muscle
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| More reference expression data |
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BioGPS | | More reference expression data |
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Gene ontology |
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Molecular function | - phosphoprotein phosphatase activity
- MAP-kinase scaffold activity
- mitogen-activated protein kinase kinase kinase binding
- phosphatase activity
- protein kinase inhibitor activity
- protein kinase activator activity
- protein binding
- protein tyrosine phosphatase activity
- hydrolase activity
- protein tyrosine/serine/threonine phosphatase activity
- JUN kinase phosphatase activity
| Cellular component | | Biological process | - negative regulation of protein kinase activity
- positive regulation of JUN kinase activity
- protein dephosphorylation
- positive regulation of JNK cascade
- negative regulation of JNK cascade
- peptidyl-tyrosine dephosphorylation
- negative regulation of JUN kinase activity
- positive regulation of MAPK cascade
- positive regulation of protein kinase activity
- dephosphorylation
- activation of protein kinase activity
- regulation of MAP kinase activity
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_001142314 NM_080876 NM_001321519 |
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RefSeq (protein) | |
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NP_001135786 NP_001308448 NP_543152 |
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Location (UCSC) | Chr 2: 183.08 – 183.1 Mb | Chr 2: 80.45 – 80.46 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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